Michael J. Smith, PhD
Professor of Cardiovascular Perfusion
Program Director of Cardiovascular Perfusion
BS, MS, PhD, University of Waterloo, Ontario, Canada
Research projects, in collaboration with faculty in the Yale School of Medicine, and Yale-New Haven Hospital, have focused on the mechanisms of systemic inflammatory response syndrome (SIRS), and investigating the efficacy of pharmaceutical compounds being developed to attenuate the response during cardiopulmonary bypass. There have also been investigations into the application of compounds to block steps in the complement cascade which occurs when blood contacts foreign surfaces, such as plastic tubing during extracorporeal circulation.
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